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[向动物脑池内注射碱性髓磷脂蛋白后的抗体反应]

[Antibody reaction to basic myelin proteins after intracisternal administration into animals].

作者信息

Mendzheritskiĭ A M

出版信息

Vopr Med Khim. 1984 Sep-Oct;30(5):106-10.

PMID:6084891
Abstract

Pathogenetic properties of antibodies to main protein of myelin, which are responsible for initiation of demyelinization process in the central nervous system, are discussed. Development of the process is accompanied by alteration in a number of biochemical reactions. Effects of the antibodies to main protein of myelin, after their intracisternal administration, are considered in relation to activation of proteolysis, alteration of glycolipid content and the functional state of the brain.

摘要

本文讨论了针对髓鞘主要蛋白的抗体的致病特性,这些抗体是引发中枢神经系统脱髓鞘过程的原因。该过程的发展伴随着许多生化反应的改变。在脑池内注射针对髓鞘主要蛋白的抗体后,研究了其对蛋白水解激活、糖脂含量改变以及脑功能状态的影响。

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