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[儿童期甲状腺功能亢进症]

[Hyperthyroidism in childhood].

作者信息

Lombardo G, De Luca F, Trimarchi F, Bianchi C

出版信息

Pediatr Med Chir. 1983 Nov-Dec;5(6):485-92.

PMID:6085155
Abstract

Pathogenesis of Graves' disease, the most frequent cause of infantile hyperthyroidism, is not definitely clarified. The role of thyroid stimulating immunoglobulins as the cause of hyperthyroidism, goiter and exophthalmos in Graves' disease is analytically considered. Genetic factors are also discussed. The Authors report some personal clinical observations emphasizing the polymorphic clinical course of the infantile Graves' disease. The diagnostic procedures and the therapeutical management are successively analyzed. Pathogenesis and clinical picture of neonatal thyrotoxicosis and Plummer's disease, two not frequent conditions, are finally examined.

摘要

格雷夫斯病是婴儿甲状腺功能亢进最常见的病因,其发病机制尚未完全阐明。本文分析探讨了甲状腺刺激免疫球蛋白在格雷夫斯病导致甲状腺功能亢进、甲状腺肿和突眼症中所起的作用。同时也讨论了遗传因素。作者报告了一些个人临床观察结果,强调了婴儿格雷夫斯病临床过程的多态性。随后分析了诊断程序和治疗管理。最后研究了新生儿甲状腺毒症和普拉默病这两种不常见病症的发病机制和临床表现。

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