Español T, Padulles J, Prats J
Dev Biol Stand. 1977;38:331-3.
Some authors have demonstrated the cytotoxic capacity of the mother's lymphocytes against the neuroblastoma cells of the son. It is not known if that is the reason for the better prognosis of these tumors in early infancy, and it was decided to treat some similar patients with transfer factor from the mother. The conditions for the patients were: more than 2 years old, poor response to chemotherapy and/or part of the tumor not resected. 3 to 5 doses of transfer factor were administered to 3 patients 2 1/2, 4 and 6 years old. One dose was taken from 400 ml of blood and prepared as described in the literature. The patients remained without metastasis more than 1 year after the treatment.
一些作者已经证明了母亲的淋巴细胞对儿子神经母细胞瘤细胞的细胞毒性能力。目前尚不清楚这是否是这些肿瘤在婴儿早期预后较好的原因，因此决定用来自母亲的转移因子治疗一些类似的患者。患者的条件为：年龄超过2岁，对化疗反应不佳和/或部分肿瘤未切除。给3例年龄分别为2岁半、4岁和6岁的患者注射了3至5剂转移因子。一剂转移因子取自400毫升血液，并按文献所述制备。治疗后，这些患者在超过1年的时间里没有发生转移。
