Hillbom M, Wennberg A
J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):699-703. doi: 10.1136/jnnp.47.7.699.
Ten male alcoholics aged 38-72 years with clear clinical and electroneurographical signs of peripheral neuropathy were re-examined three to five years later. Conduction velocities, latencies and nerve action potential amplitudes were measured from median, peroneal and sural nerves on both occasions and the results were compared with age-matched reference values from 80 healthy men. Seven of the alcoholics showed normal or nearly normal scores in electroneurographical and clinical examination and they had all managed to stop drinking alcohol. The results suggest that the prognosis of alcoholic peripheral neuropathy is good and independent of age provided that intake of alcohol is discontinued and other causes of neuropathy (malignancy, diabetes, nerve trauma) are carefully excluded.
10名年龄在38至72岁之间、有明确临床和神经电图表现的周围神经病变的男性酗酒者在三到五年后接受了复查。两次均测量了正中神经、腓总神经和腓肠神经的传导速度、潜伏期和神经动作电位幅度,并将结果与80名健康男性的年龄匹配参考值进行了比较。7名酗酒者在神经电图和临床检查中显示正常或接近正常分数,并且他们都成功戒酒。结果表明,只要停止饮酒并仔细排除神经病变的其他原因(恶性肿瘤、糖尿病、神经创伤),酒精性周围神经病变的预后良好且与年龄无关。