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喉呼吸运动神经元:兴奋性和抑制性突触输入的不同位点的形态学和电生理学证据。

Laryngeal respiratory motoneurones: morphology and electrophysiological evidence of separate sites for excitatory and inhibitory synaptic inputs.

作者信息

Barillot J C, Bianchi A L, Gogan P

出版信息

Neurosci Lett. 1984 Jun 15;47(2):107-12. doi: 10.1016/0304-3940(84)90414-2.

DOI:10.1016/0304-3940(84)90414-2
PMID:6087221
Abstract

Activities of respiratory laryngeal motoneurones were recorded intracellularly in the nucleus ambiguus of the cat. Some of them were intracellularly injected with peroxidase for morphological reconstruction. Stimulation of the superior laryngeal nerve (SLN) evoked excitatory responses in both somata and axons of expiratory laryngeal motoneurones. In inspiratory laryngeal motoneurones, the responses induced by the SLN depended on the site of recording: inhibition and decrease of excitatory input in somata, excitation in axons. We conclude that excitatory synaptic effects of SLN stimulation acts mainly on, or close to, the initial segment of inspiratory motoneurones, while inhibition reaches the somato-dendritic region.

摘要

在猫的疑核中对呼吸喉运动神经元的活动进行了细胞内记录。其中一些神经元被细胞内注射过氧化物酶以进行形态重建。刺激喉上神经(SLN)可在呼气性喉运动神经元的胞体和轴突中诱发兴奋性反应。在吸气性喉运动神经元中,SLN诱发的反应取决于记录部位:胞体中兴奋性输入的抑制和减少,轴突中的兴奋。我们得出结论,SLN刺激的兴奋性突触效应主要作用于吸气运动神经元的起始段或其附近,而抑制作用则到达胞体-树突区域。

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