Vidt D G
Urol Clin North Am. 1984 Aug;11(3):417-24.
Although clinical reports have suggested that antihypertensive therapy can control blood pressure in patients with renovascular hypertension, adequate randomized studies comparing medical versus surgical management are lacking. It is well recognized that progressive deterioration in renal function can occur despite good blood pressure control. Recent experience suggests that higher-risk patients with atherosclerotic renovascular hypertension can benefit from an aggressive surgical approach, whereas newer medical therapies capable of specific inhibition of the renin-angiotensin system suggest greater potential benefits to other patients. Properly performed randomized trials comparing medical versus surgical therapy of renovascular hypertension are needed.
尽管临床报告表明抗高血压治疗可以控制肾血管性高血压患者的血压，但缺乏比较药物治疗与手术治疗的充分随机研究。人们普遍认识到，尽管血压得到良好控制，但肾功能仍可能逐渐恶化。最近的经验表明，高危的动脉粥样硬化性肾血管性高血压患者可从积极的手术治疗中获益，而能够特异性抑制肾素-血管紧张素系统的新型药物疗法对其他患者显示出更大的潜在益处。因此需要进行恰当的随机试验来比较肾血管性高血压的药物治疗与手术治疗。
