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[Immunity indices of mice immunized with different vaccines against Japanese encephalitis].

作者信息

Pervikov Iu V, El'bert L B, Karaseva P S, Lisitsina E A

出版信息

Vopr Virusol. 1984 May-Jun;29(3):337-42.

PMID:6087567
Abstract

The test of adoptive transfer of immunity demonstrated that in the mice vaccinated with inactivated Japanese encephalitis vaccines the protective activity to the homologous virus is provided predominantly by B-lymphocytes the protective effect of which is enhanced by cooperative interaction with T-lymphocytes. The culture (CV) and purified brain (BV) vaccines induce high levels of humoral and cell-mediated immunity, however, the capacity of CV to produce antibody is higher than that of BV. Both preparations do not cause in vaccinated mice any changes in responsiveness to extraneous antigen (sheep red cells), or disorders in chemotaxic mobility of leukocytes and phagocytic activity of macrophages.

摘要

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