维生素D3活性代谢产物作为运动不足大鼠钙磷代谢紊乱的一种应对措施。
Vitamin D3 active metabolites as a countermeasure against disorders of calcium-phosphorus metabolism in hypokinetic rats.
作者信息
Ushakov A S, Spirichev V B, Belakovsky M S, Sergeev I N, Kaplansky A S, Shvets V N
出版信息
Aviat Space Environ Med. 1984 Jun;55(6):534-7.
PMID:6087784
Abstract
Male Wistar rats that were experimentally hypokinetic were fed 24,25(OH)2D3 or 1,25(OH)2D3 separately or in combination to determine the effect on bone growth and on bone formation and resorption. It was shown that these parameters of bone metabolism are influenced by these metabolites of vitamin D3 by their effect on bone sensitivity to their activity and perhaps in the regulation of bone histogenesis.
摘要
对实验性运动不足的雄性Wistar大鼠分别或联合喂食24,25(OH)₂D₃或1,25(OH)₂D₃，以确定其对骨骼生长以及骨形成和骨吸收的影响。结果表明，骨代谢的这些参数受维生素D₃的这些代谢产物影响，其作用机制可能是影响骨骼对其活性的敏感性，或许还参与了骨组织发生的调节。
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