人单核细胞上的腺苷A2受体调节C2生成。
Adenosine A2 receptors on human monocytes modulate C2 production.
作者信息
Lappin D, Whaley K
出版信息
Clin Exp Immunol. 1984 Aug;57(2):454-60.
Abstract
Adenosine inhibits C2 production by human monocytes. The use of synthetic analogues of adenosine suggested that the action was mediated by receptors of A2 type. EHNA which inhibits the enzyme adenosine deaminase and increases the concentration of intracellular adenosine also reduces C2 production. It is therefore possible that endogenous adenosine regulates C2 synthesis.
摘要
腺苷可抑制人单核细胞产生C2。腺苷合成类似物的应用表明，该作用是由A2型受体介导的。抑制腺苷脱氨酶并提高细胞内腺苷浓度的EHNA也能降低C2的产生。因此，内源性腺苷有可能调节C2的合成。
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