Campanacci M, De Sessa L, Trentani C
Ital J Orthop Traumatol. 1977 Apr;3(1):27-36.
The results of 30 consecutive cases of simple bone cysts treated conservatively by intracystic injections of methylprednisolone acetate (MPA) according to the method of Scaglietti are reported. The injections were given under general or local anaesthesia in doses of 80-200 mgs repeated every 2 months up to a total of 2 or 3 injections, rarely more. The minimum period required for achieving a result is 6 months; but there is a continuation of radiographic improvement for 1 to 2 years. There is complete radiographic cure in about half the cases; in the others there is a substantial improvement which makes surgery unnecessary. We have used this method systematically for 3 years, and out of 42 cases only one required operation because of a displaced subtrochanteric fracture. There was a partial recurrence in one case after apparent radiographic cure. The patients' age does not seem to affect the result but we gained the impression that the effect of MPA is quicker and more reliable in younger patients. Although we do not understand the mechanism of cure in this method it has undoubted advantages over surgery.
报告了30例采用斯卡列蒂方法经囊内注射醋酸甲泼尼龙（MPA）保守治疗单纯性骨囊肿的连续病例结果。注射在全身麻醉或局部麻醉下进行，剂量为80 - 200毫克，每2个月重复一次，总共注射2或3次，很少超过3次。取得疗效所需的最短时间为6个月；但放射学改善会持续1至2年。约一半的病例实现了放射学完全治愈；其他病例有显著改善，无需进行手术。我们系统地使用这种方法3年，42例中只有1例因转子下骨折移位而需要手术。1例在放射学上明显治愈后出现部分复发。患者年龄似乎不影响治疗结果，但我们感觉MPA在年轻患者中的效果更快且更可靠。尽管我们不了解这种治疗方法的治愈机制，但它相对于手术无疑具有优势。
