Burmeister W
Monatsschr Kinderheilkd. 1984 Jul;132(7):556-7.
Cholecalciferol (CC) given orally is not utilized as efficiently as the CC produced by cutaneous UV light. The infant receives only minute amounts of CC by breast feeding, abolishing therefore the role of a vitamin for CC. The most important D-metabolite of human milk, the calcifediol (CF), however, has transient vitamin character. CF is both resorbed more efficiently by the intestine and it effects mineral metabolism faster via kidney than CC, which needs hydroxylation in the liver first. Thus CF shows advantages in prophylaxis and therapy. However, different (lower) dosages and the danger of hypercalcemia should be kept in mind using CF.
口服胆钙化醇（CC）的利用效率不如皮肤经紫外线照射产生的CC。婴儿通过母乳喂养仅获得微量的CC，因此消除了维生素对CC的作用。然而，人乳中最重要的D代谢产物骨化二醇（CF）具有短暂的维生素特性。CF在肠道中的吸收效率更高，并且它通过肾脏对矿物质代谢的影响比CC更快，CC首先需要在肝脏中进行羟基化。因此，CF在预防和治疗方面具有优势。然而，使用CF时应牢记不同（较低）的剂量和高钙血症的风险。
