Shvareva N V
Probl Endokrinol (Mosk). 1984 Jul-Aug;30(4):25-31.
The activity of endocrine glands of 20- to 34-year-old women, living in Magadan, has been studied to determine the role of the endocrine system in adaptation mechanisms of man under conditions of the north regions. Thyroxine, triiodothyronine, thyroglobulin, hypophyseal thyrotrophic and gonadotrophic hormone, prolactin, cortisol and corticotrophin concentrations in the peripheral blood of 475 healthy females were measured by radioimmunoassay at different times of their arrival to the North. The most tense periods in the long-term adaptation are the first three years after the removal from the Central regions of the country and prolonged living in the North (over 10 years), when the average indices of basal secretion of the adrenocortical, thyroid and hypophyseal hormones markedly vary, the range of the blood hormone concentrations and the amplitude of individual variations increase, the functional relationship between several components of the endocrine system is strengthened. In representative of the 1st generation of the newly arrived women the hormonal background is characterized by high cortisol and gonadotrophic hormone concentrations. The data obtained indicate that complex hormonal reconstructions occur in the endocrine system during the process of prolonged adaptation, persisting during the whole period of living in the north regions.
为了确定内分泌系统在北方地区条件下人类适应机制中的作用，对居住在马加丹的20至34岁女性的内分泌腺活动进行了研究。通过放射免疫分析法在475名健康女性抵达北方的不同时间测量其外周血中甲状腺素、三碘甲状腺原氨酸、甲状腺球蛋白、垂体促甲状腺激素和促性腺激素、催乳素、皮质醇和促肾上腺皮质激素的浓度。长期适应过程中最紧张的时期是从该国中部地区迁移后最初三年以及在北方长期居住（超过10年）时，此时肾上腺皮质、甲状腺和垂体激素基础分泌的平均指标明显变化，血液激素浓度范围和个体差异幅度增加，内分泌系统几个组成部分之间的功能关系增强。第一代新抵达女性的激素背景特征是皮质醇和促性腺激素浓度较高。所获得的数据表明，在长期适应过程中内分泌系统会发生复杂的激素重构，并且在整个居住在北方地区的期间持续存在。
