离子通过神经膜上固定孔隙的移动。
Movement of ions through fixed pores in the neural membrane.
作者信息
Wooldridge D E
出版信息
Proc Natl Acad Sci U S A. 1984 Sep;81(17):5609-12. doi: 10.1073/pnas.81.17.5609.
Abstract
A simple configuration is first proposed for the pores used by sodium and potassium ions in moving through the neural membrane. The voltage dependence of the ion current through a system of such pores is then derived from diffusion theory and shown not to agree well with experimental observation. Good agreement is obtained, however, when the end segments of the pores are modified to include constrictions and ion-specific trapping centers.
摘要
首先提出了一种用于钠离子和钾离子通过神经膜的孔的简单构型。然后根据扩散理论推导了通过这种孔系统的离子电流的电压依赖性，结果表明与实验观察结果不太吻合。然而，当对孔的末端部分进行修改，使其包含收缩部分和离子特异性俘获中心时，就得到了很好的吻合。
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J Physiol. 1952 Apr;116(4):473-96. doi: 10.1113/jphysiol.1952.sp004718.
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J Physiol. 1952 Apr;116(4):449-72. doi: 10.1113/jphysiol.1952.sp004717.
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A spike-forming model of the neural membrane.神经膜的一个形成尖峰的模型。
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