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[舒必利一项此前未发表的适应症:功能性子宫出血]

[A previously unpublished indication for sulpiride: functional uterine hemorrhages].

作者信息

Trévoux R

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1977 Dec;6(8):1133-8.

PMID:608930
Abstract

Sulpiridin has been shown to be remarkably efficient in treating functional uterine haemorrhage (70 per cent success). It is especially so in the pre-menopause. Its mode of action takes place on three levels: the hypothalamus, where it works on the clonic centre for the release of gonadotrophins (the tonic centre not being affected); the ovaries, where it lessens the sensitivity of the reaction of the ovary to gonadotrophins; the uterus, where there is direct action on the thickness of the mucous lining of the uterus and on its blood supply.

摘要

舒必利已被证明在治疗功能性子宫出血方面非常有效(成功率达70%)。在绝经前尤其如此。其作用方式体现在三个层面:下丘脑,它作用于促性腺激素释放的阵挛中枢(紧张中枢不受影响);卵巢,它降低卵巢对促性腺激素反应的敏感性;子宫,它对子宫内膜厚度及其血液供应有直接作用。

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