Manavalan P, Johnson W C, Modrich P
J Biol Chem. 1984 Oct 10;259(19):11666-7.
The circular dichroism of Eco RI restriction endonuclease was measured to 178 nm and analyzed for secondary structure. The results (33% alpha-helix, 25% beta-sheet, 17% turns, and 25% other structures) compare well with our joint prediction from sequence data.
