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膈运动神经元的单突触抑制:来自包钦格复合体神经元的长下行投射。

Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Bötzinger neurons.

作者信息

Merrill E G, Fedorko L

出版信息

J Neurosci. 1984 Sep;4(9):2350-3. doi: 10.1523/JNEUROSCI.04-09-02350.1984.

Abstract

Synaptic connections between medullary expiratory neurons and phrenic motoneurons were studied in anesthetized cats using spike-triggered averaging of synaptic noise in phrenic motoneurons. Monosynaptic inhibition of phrenic motoneurons originating from the rostral medullary expiratory neurons of the Bötzinger complex was revealed. Neither mono- nor disynaptic inhibition from expiratory neurons of the nucleus retroambigualis was found. It was concluded that Bötzinger complex expiratory neurons make long descending inhibitory connections with phrenic motoneurons: the expiratory neurons of the nucleus retroambigualis do not appear to make synaptic connections with phrenic motoneurons.

摘要

在麻醉猫中,使用膈运动神经元突触噪声的触发尖峰平均法,研究了延髓呼气神经元与膈运动神经元之间的突触连接。发现源自包钦格复合体嘴侧延髓呼气神经元的膈运动神经元存在单突触抑制。未发现来自疑核尾部呼气神经元的单突触或双突触抑制。得出的结论是,包钦格复合体呼气神经元与膈运动神经元形成长距离下行抑制性连接:疑核尾部的呼气神经元似乎不与膈运动神经元形成突触连接。

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