γ-氨基丁酸能传递中的多种信号：药理学后果 - Suppr | 超能文献

Multiple signals in GABAergic transmission: pharmacological consequences.

作者信息

Costa E, Ferrari M, Ferrero P, Guidotti A

出版信息

Neuropharmacology. 1984 Aug;23(8):989-91. doi: 10.1016/0028-3908(84)90016-9.

DOI:10.1016/0028-3908(84)90016-9

Abstract

摘要

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Multiple signals in GABAergic transmission: pharmacological consequences.γ-氨基丁酸能传递中的多种信号：药理学后果

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[Drug activation of GABAergic transmission in the central nervous system: benzodiazepines and GABAergic agonists].

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Are benzodiazepine recognition sites functional entities for the action of endogenous effector(s) or merely drug receptor(s)?苯二氮䓬识别位点是内源性效应物作用的功能实体，还是仅仅是药物受体？

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Endogenous ligands for benzodiazepine recognition sites.

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In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates.通过正电子发射断层扫描在非人灵长类动物中评估苯二氮䓬受体配体对γ-氨基丁酸能传递的体内双向调节作用。

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Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex.异烟肼，一种γ-氨基丁酸能传递的抑制剂，可增强大鼠大脑皮层中[35S]TBPS的结合。

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Enhancement of GABA binding by benzodiazepines and related anxiolytics.苯二氮䓬类药物及相关抗焦虑药对γ-氨基丁酸（GABA）结合的增强作用。

Eur J Pharmacol. 1983 May 6;89(3-4):193-8. doi: 10.1016/0014-2999(83)90494-6.

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Modulation of GABAergic transmission by ethanol.

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Reduction of inhibition by a benzodiazepine antagonist, Ro15-1788, in the rat hippocampal slice.

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Microgram doses of diazepam do not induce proconvulsant or proconflict effects in rodents.微克剂量的地西泮不会在啮齿动物中诱发惊厥前或冲突前效应。

Psychopharmacology (Berl). 1987;93(3):389-92. doi: 10.1007/BF00187262.

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Purification of a benzodiazepine from bovine brain and detection of benzodiazepine-like immunoreactivity in human brain.从牛脑中纯化一种苯二氮䓬并检测人脑中苯二氮䓬样免疫反应性。

Proc Natl Acad Sci U S A. 1986 Dec;83(23):9236-40. doi: 10.1073/pnas.83.23.9236.

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Demonstration of benzodiazepine-like molecules in the mammalian brain with a monoclonal antibody to benzodiazepines.用抗苯二氮䓬类单克隆抗体在哺乳动物大脑中证明苯二氮䓬类分子的存在。

Proc Natl Acad Sci U S A. 1985 Aug;82(16):5560-4. doi: 10.1073/pnas.82.16.5560.