Virgolini L
Minerva Med. 1984 Jul 31;75(30-31):1797-802.
Acute promyelocytic leukemia is characterized by bone marrow infiltration with hypergranular promyelocytes, often with Auer bodies. Clinically it is characterized by a hemorrhagic syndrome caused by a disseminated intravascular coagulation. Karyotypic studies have shown a frequent translocation t(15;17). Improved prognosis resulted from chemotherapy with DAT and treatment with heparin.
急性早幼粒细胞白血病的特征是骨髓被颗粒增多的早幼粒细胞浸润，常可见奥氏小体。临床上其特征为弥散性血管内凝血所致的出血综合征。染色体组型研究显示常有15号与17号染色体易位。联合化疗及肝素治疗改善了预后。
