Cleemann L, Pizarro G, Morad M
Science. 1984 Oct 12;226(4671):174-7. doi: 10.1126/science.6091269.
The impermeant dye antipyrylazo III was used to measure depletion of extracellular calcium and net influx of calcium through the sarcolemma during the cardiac action potential. It was found that calcium entry occurs continuously during the action potential and is under direct control of the membrane potential. The inotropic action of epinephrine is accompanied by increased influx of calcium, while strophanthidin enhances the twitch without altering calcium influx during the action potential.
使用非渗透性染料安替比拉宗III来测量心脏动作电位期间细胞外钙的消耗以及通过肌膜的钙净内流。结果发现，在动作电位期间钙持续内流，且受膜电位的直接控制。肾上腺素的变力作用伴随着钙内流增加，而毒毛花苷增强了抽搐，但在动作电位期间不改变钙内流。
