Eelkema E A, Stephens D H, Ward E M, Sheedy P F
AJR Am J Roentgenol. 1984 Nov;143(5):943-8. doi: 10.2214/ajr.143.5.943.
To determine the computed tomographic (CT) characteristics of nonfunctioning islet cell carcinoma of the pancreas, the CT scans of 27 patients with that disease were reviewed. The pancreatic tumor was identified as a mass in 26 patients (96%). Demonstrated masses were 3-24 cm in diameter. Eight of the tumors (31%) were larger than 10 cm. Six tumors (22%) contained calcification. Of the 25 tumors evaluated with contrast enhancement, 20 became partially or diffusely hyperdense relative to nearby normal pancreatic tissue. Hepatic metastases were identified in 15 patients (56%), regional lymphadenopathy in 10 (37%), atrophy of the gland proximal to the tumor in six (22%), dilatation of the biliary ducts in five (19%), and dilatation of the pancreatic duct in four (15%). The CT appearances of the nonfunctioning islet cell tumors were compared with those of 100 ordinary (ductal) pancreatic adenocarcinomas. Although the two types of tumors were sometimes indistinguishable, features found to be more characteristic of islet cell carcinoma included a pancreatic mass of unusually large size, calcification within the tumor, and contrast enhancement of either the primary tumor or hepatic metastases. Involvement of the celiac axis or proximal superior mesenteric artery was limited to ductal carcinoma.
为了确定胰腺无功能胰岛细胞瘤的计算机断层扫描（CT）特征，我们回顾了27例该病患者的CT扫描结果。26例患者（96%）的胰腺肿瘤表现为肿块。显示的肿块直径为3 - 24厘米。其中8个肿瘤（31%）直径大于10厘米。6个肿瘤（22%）有钙化。在25个接受对比增强评估的肿瘤中，20个相对于附近正常胰腺组织出现部分或弥漫性高密度。15例患者（56%）发现肝转移，10例（37%）有区域淋巴结肿大，6例（22%）肿瘤近端腺体萎缩，5例（19%）胆管扩张，4例（15%）胰管扩张。将无功能胰岛细胞瘤的CT表现与100例普通（导管）胰腺腺癌的表现进行了比较。尽管这两种肿瘤有时难以区分，但发现更具胰岛细胞癌特征的表现包括异常大的胰腺肿块、肿瘤内钙化以及原发肿瘤或肝转移的对比增强。腹腔动脉或肠系膜上动脉近端受累仅限于导管癌。
