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[鉴定N,N-二甲基-O-(β-D-吡喃葡萄糖醛酸基)-5-羟色胺为家兔蟾蜍色胺的一种代谢产物]

[Identification of N,N-dimethyl-O-(beta-D-glucopyranuronosyl)-5- hydroxytryptamine as a bufotenine metabolite in the rabbit].

作者信息

Vigdorchik M M, Turchin K F, Gus'kova T A, Iakubovich L M, Krasavina L S

出版信息

Bioorg Khim. 1984 Feb;10(2):260-4.

PMID:6091679
Abstract

A bufotenine metabolite has been isolated from the rabbit urine by the column chromatography on cellulose and preparative paper electrophoresis in acidic buffer. It has the structure of N,N-dimethyl-O-(beta-D-glucopyranuronosyl)-5-hydroxytryptamine as proved by comparison of chromatographic, electrophoretic and NMR data with those for respective synthetic O-glucuronide.

摘要

通过在纤维素上进行柱色谱法以及在酸性缓冲液中进行制备性纸电泳,已从兔尿中分离出一种蟾蜍色胺代谢物。通过将色谱、电泳和核磁共振数据与相应合成O-葡糖醛酸苷的数据进行比较,证明其结构为N,N-二甲基-O-(β-D-吡喃葡糖醛酸基)-5-羟色胺。

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