Sadik A R, Port R, Garfinkel B, Bravo J
Neurosurgery. 1984 Oct;15(4):549-51. doi: 10.1227/00006123-198410000-00014.
A patient with glioblastoma multiforme of the right cerebral hemisphere that was treated by surgical removal followed by cobalt therapy is presented. The patient's only neurological deficit at the initial presentation had been a left homonymous hemianopsia, which remained unchanged after operation. He had maintained a good functional state for about 18 months. Then, because of low backache, he was restudied thoroughly, and a bony destructive lesion was found in the body of the 4th lumbar vertebra. A computed tomographic scan-guided biopsy of this lesion revealed a histopathological picture similar to that of the primary cerebral glioma. This metastatic glioma of the spine was treated with cobalt therapy with good clinical (i.e., pain relief) response. The case represents extracranial metastasis of cerebral glioblastoma, which is rarely seen. A brief review of the literature and of the theories concerning dissemination is presented.
本文介绍了一名患有右大脑半球多形性胶质母细胞瘤的患者，该患者接受了手术切除并随后进行了钴治疗。患者初次就诊时唯一的神经功能缺损为左侧同向性偏盲，术后保持不变。他保持良好的功能状态约18个月。然后，由于腰痛，对他进行了全面复查，在第四腰椎体发现了一个骨质破坏病变。对该病变进行计算机断层扫描引导下活检，显示组织病理学图像与原发性脑胶质瘤相似。这种脊柱转移性胶质瘤接受了钴治疗，临床反应良好（即疼痛缓解）。该病例代表脑胶质母细胞瘤的颅外转移，这种情况很少见。本文还对相关文献及有关播散的理论进行了简要综述。
