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[阿片类药物调节疼痛的机制:下行通路。批判性综述]

[Opioid mechanisms for modulating pain: descending pathways. Critical review].

作者信息

Bertagna G, Della Porta L, Spadafora R, Bernabei A

出版信息

Riv Neurol. 1984 Jul-Aug;54(4):217-34.

PMID:6093228
Abstract

This paper presents an extensive review of contributions on opiate controlled descending projections modulating analgesia. While there is a quite definite agreement on the organisation and structure of these projections, their true physiological role remains quite dubious. The hypothesis so far formulated on the modalities of activation of these circuits apparently don't hold a critical re-examination.

摘要

本文对阿片类物质调控下行投射调节镇痛的相关研究进行了全面综述。虽然关于这些投射的组织和结构已有明确共识,但其真正的生理作用仍颇具争议。目前针对这些回路激活方式所提出的假说显然经不起严格的重新审视。

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