Berninger T, Becker H, Vitzthum H G
Strahlentherapie. 1984 Sep;160(9):549-56.
33 patients with primary and secondary brain tumours received radiotherapy. The therapeutic success was computer tomographically controlled. Only a temporary reduction in the size of the tumour could be observed during the radiotherapy. In connection with the reduction of the pathological findings in the CT, an improvement in the neurological findings was determined. A change in the tumour absorption may occur under the radiotherapy. An important indicator for tumour growth or regression is the change in the tumour absorption in computed tomography with the contrast medium. If the enhancement remains inspite of the radiotherapy, it can prognostically be considered as a detrimental factor. In the case of 10 of the 33 patients undergoing radiotherapy the tumour became isodense. No more enhancement was detectable. Isodensity may not be seen as a complete normalization of the brain tissue as could be established by histological investigations. On the other hand if again hypodense areas are revealed, it does not necessarily mean recurrence of tumour. Such an hypodense region then implies a radiogenic tumour-necrosis. Only the renewed enhancement after administering of the contrast medium in the area of the tumour must be considered as recurrence.
33例原发性和继发性脑肿瘤患者接受了放射治疗。治疗效果通过计算机断层扫描进行监测。放疗期间仅观察到肿瘤大小暂时缩小。结合CT上病理表现的减轻，神经学表现有所改善。放疗过程中肿瘤吸收可能发生变化。计算机断层扫描增强扫描时肿瘤吸收的变化是肿瘤生长或消退的重要指标。如果放疗后强化仍然存在，从预后角度可将其视为不利因素。在接受放疗的33例患者中，有10例肿瘤变为等密度，未检测到进一步强化。等密度并不意味着脑组织完全恢复正常，这可通过组织学检查确定。另一方面，如果再次出现低密度区，并不一定意味着肿瘤复发。这样的低密度区意味着放射性肿瘤坏死。只有在肿瘤区域注射造影剂后再次出现强化才应视为复发。
