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[莫斯科动物园类人猿中的甲型和乙型病毒性肝炎]

[Viral hepatitis A and B in anthropoid apes of the Moscow Zoo].

作者信息

Anan'ev V A, Viazov S O, Garanina N M, Doroshenko N V, Zhilina N N

出版信息

Vopr Virusol. 1984 Jul-Aug;29(4):434-7.

PMID:6093384
Abstract

The rate of occurrence of hepatitis A and B virus specific markers in anthropoid apes of the Moscow Zoo (3 chimpanzees, 3 gorillas, 8 orang-outangs) was studied. Long-term persistence of HBs-antigen in orang-outang accompanied by the presence of HBe-antigen and anti-HBs was demonstrated. The presence of anti-HBs in gorillas and orang-outangs was recorded. Antibodies to hepatitis A virus were found in all the animal species examined. Cases of acute virus hepatitis A in orang-outangs are described contracted from the personnel handling the animals and suffering from this type of hepatitis. Morphological features of the course of hepatitis A in the presence of HBs-antigen carrier state are described. The possibility of active immunization of susceptible animals and the personnel of the zoo against viral hepatitides is discussed.

摘要

对莫斯科动物园的类人猿(3只黑猩猩、3只大猩猩、8只猩猩)中甲型和乙型肝炎病毒特异性标志物的出现率进行了研究。结果表明,猩猩体内乙肝表面抗原长期持续存在,并伴有乙肝e抗原和乙肝表面抗体。在大猩猩和猩猩体内检测到了乙肝表面抗体。在所有检测的动物物种中均发现了甲型肝炎病毒抗体。描述了猩猩感染甲型急性病毒性肝炎的病例,这些病例是由患有此类肝炎的动物饲养人员传染所致。描述了在乙肝表面抗原携带状态下甲型肝炎病程的形态学特征。讨论了对易感动物和动物园工作人员进行病毒性肝炎主动免疫的可能性。

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