Sly P D, Soto-Quiros M E, Landau L I, Hudson I, Newton-John H
Arch Dis Child. 1984 Oct;59(10):935-9. doi: 10.1136/adc.59.10.935.
Adenoviruses are well known causes of respiratory illness in children. Long term sequelae reported with types 3, 7, and 21 include bronchiolitis obliterans, bronchiectasis, and the hyperlucent lung or McLeod syndrome. Twenty children admitted to hospital with adenovirus type 7 pneumonia between 1960 and 1978 were studied and compared with 20 controls admitted during the same period with adenovirus type 7 upper respiratory tract infections. Sixty five per cent of the pneumonia group had developed evidence of airways obstruction compared with 10% of controls. Young age at the time of pneumonia and a 'measles-like' illness before its onset increase the chance of developing long term pulmonary function abnormalities. Sex and family history of smoking or atopy do not influence outcome.
腺病毒是儿童呼吸道疾病的常见病因。据报道，3型、7型和21型腺病毒感染的长期后遗症包括闭塞性细支气管炎、支气管扩张以及肺透亮增强或麦克劳德综合征。对1960年至1978年间因7型腺病毒肺炎入院的20名儿童进行了研究，并与同期因7型腺病毒上呼吸道感染入院的20名对照儿童进行了比较。肺炎组65%出现气道阻塞迹象，而对照组为10%。肺炎发病时年龄较小以及发病前出现“麻疹样”疾病会增加发生长期肺功能异常的几率。性别以及吸烟或特应性家族史不影响预后。
