Shitov L A, Viru A A
Biull Eksp Biol Med. 1984 Oct;98(10):391-3.
The time-course of changes in the blood corticotropin and cortisol concentration was studied in 9 dogs during standing with a load on the back. The pituitary-adrenocortical system was shown to be activated fairly rapidly. The initially occurring rise in corticotropin concentration was coupled with a more prolonged elevation of blood cortisol. In the absence of cortisol from the blood which was caused by long-term injection of chloditan, activation of corticotropic function proceeded more intensely whereas the reduction in corticotropin concentration after its initial increment was less demonstrable as compared to that seen in normal adrenal function.
研究了9只狗在背负负荷站立时血中促肾上腺皮质激素和皮质醇浓度的变化时间过程。结果表明垂体 - 肾上腺皮质系统被相当迅速地激活。促肾上腺皮质激素浓度最初的升高与血皮质醇更持久的升高相关。在长期注射氯地孕酮导致血液中皮质醇缺乏的情况下，促肾上腺皮质功能的激活更为强烈，而与正常肾上腺功能相比，促肾上腺皮质激素浓度在最初升高后的降低不太明显。
