通过使用针对从人类嗜T细胞病毒I型（HTLV-I）的X-IV DNA序列和HTLV-II前病毒的Xc DNA序列推导的肽段的抗体，检测HTLV感染细胞中的pX蛋白。
Detection of pX proteins in human T-cell leukemia virus (HTLV)-infected cells by using antibody against peptide deduced from sequences of X-IV DNA of HTLV-I and Xc DNA of HTLV-II proviruses.
作者信息
Miwa M, Shimotohno K, Hoshino H, Fujino M, Sugimura T
出版信息
Gan. 1984 Sep;75(9):752-5.
PMID:6094296
Abstract
A 41-kilodalton protein was detected in four human T-cell leukemia virus type I (HTLV-I)-infected cell lines, a 68-kilodalton glycoprotein in MT-2 cells, and a 38-kilodalton protein in an HTLV-II-infected cell line by using antibody against a synthetic dodecapeptide, a portion of the polypeptide deduced from the nucleotide sequence of the X regions of HTLVs.
摘要
通过使用针对合成十二肽（从人类嗜T细胞病毒（HTLV）X区域核苷酸序列推导的多肽的一部分）的抗体，在四种I型人类嗜T细胞病毒（HTLV-I）感染的细胞系中检测到一种41千道尔顿的蛋白质，在MT-2细胞中检测到一种68千道尔顿的糖蛋白，在一种II型人类嗜T细胞病毒（HTLV-II）感染的细胞系中检测到一种38千道尔顿的蛋白质。
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