Suzuki Y, Gojobori T
Center for Information Biology, National Institute of Genetics, Mishima, Japan.
Virus Genes. 1998;16(1):69-84. doi: 10.1023/a:1007953826869.
Studies on human T-cell lymphotropic virus types I (HTLV-I) and II (HTLV-II) are briefly reviewed from the viewpoint of molecular evolution, with special reference to the evolutionary rate and evolutionary relationships among these viruses. In particular, it appears that, in contrast to the low level of variability of HTLV-I among different isolates, individual isolates form quasispecies structures. Elucidating the mechanisms connecting these two phenomena will be one of the future problems in the study of the molecular evolution of HTLV-I and HTLV-II.
从分子进化的角度对人类嗜T细胞病毒I型（HTLV-I）和II型（HTLV-II）的研究进行简要综述，特别提及这些病毒的进化速率和进化关系。尤其值得注意的是，与不同分离株中HTLV-I的低变异性相反，单个分离株形成了准种结构。阐明连接这两种现象的机制将是HTLV-I和HTLV-II分子进化研究未来面临的问题之一。
