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大肠杆菌K-12中recA441对recF143的双组分抑制作用。

Two-component suppression of recF143 by recA441 in Escherichia coli K-12.

作者信息

Volkert M R, Margossian L J, Clark A J

出版信息

J Bacteriol. 1984 Nov;160(2):702-5. doi: 10.1128/jb.160.2.702-705.1984.

Abstract

Sensitivity to UV irradiation conferred by recF143 was partially suppressed by recA441 (also known as tif-1). A temperature-conditional component depended on uvrA function and is thought to involve thermal induction of excision repair enzymes. In a uvrA6 mutant, a temperature-independent component of suppression was seen. This is thought to indicate that recA441 also caused temperature-independent changes in recA activity. Two hypotheses are offered to explain how recA441 produced both thermosensitive and thermoindependent effects.

摘要

recF143赋予的对紫外线照射的敏感性被recA441(也称为tif-1)部分抑制。一个温度条件成分依赖于uvrA功能,并且被认为涉及切除修复酶的热诱导。在uvrA6突变体中,观察到了一种与温度无关的抑制成分。这被认为表明recA441也导致了recA活性的与温度无关的变化。提出了两个假说来解释recA441如何产生热敏和与温度无关的效应。

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本文引用的文献

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