舒巴坦/头孢哌酮在妇产科领域的临床研究
[Clinical studies of sulbactam/cefoperazone in the field of obstetrics and gynecology].
作者信息
Fukuda O, Shimokawa K, Inoue S, Maeyama M
出版信息
Jpn J Antibiot. 1984 Oct;37(10):1977-82.
Sulbactam (SBT), a new beta-lactamase inhibitor, in combination with cefoperazone (CPZ) was studied for the clinical evaluation in the field of obstetrics and gynecology. SBT/CPZ was given to 6 cases with the following infections; 4 of pyometra, 1 of Douglas-abscess and 1 of pelvic cellulitis. Five cases were old patients accompanied by cancers, and 2 cases were refractory to other antibiotics therapy. The clinical efficacy was excellent in 1 case, good in 3 cases, poor in 2 cases. No side effects nor abnormal laboratory findings associate with the agent were observed.
舒巴坦（SBT）是一种新型β-内酰胺酶抑制剂，与头孢哌酮（CPZ）联合应用于妇产科领域进行临床评估。对6例患有以下感染的患者给予舒巴坦/头孢哌酮治疗：4例脓性子宫炎、1例Douglas窝脓肿和1例盆腔蜂窝织炎。5例为伴有癌症的老年患者，2例对其他抗生素治疗无效。临床疗效为优1例，良3例，差2例。未观察到与该药物相关的副作用及实验室检查异常。
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