Doko F
Jpn J Antibiot. 1984 Nov;37(11):2243-50.
Sulbactam (SBT), a new beta-lactamase inhibitor, in combination with cefoperazone (CPZ) to 1 to 1 was clinically studied in the field of obstetrics and gynecology. SBT/CPZ was administered to 13 subjects at a daily dose of 2 g in 2 divided dose by intravenous infusion for 4-6 days. The subjects were patients with the following infections: 2 of intrauterine infections, 5 of intrapelvic infections, 4 of adnexitis and 2 of vulvar infections. The overall clinical efficacy was good in all. Neither adverse reactions nor abnormal laboratory findings were observed in any of the cases.
舒巴坦(SBT)是一种新型β-内酰胺酶抑制剂,与头孢哌酮(CPZ)按1:1联合应用,在妇产科领域进行了临床研究。对13例受试者静脉滴注舒巴坦/头孢哌酮,每日剂量2g,分2次给药,疗程4 - 6天。受试者为患有以下感染的患者:宫内感染2例、盆腔内感染5例、附件炎4例、外阴感染2例。总体临床疗效良好。所有病例均未观察到不良反应及实验室检查异常。