Kharchenko V P, Chkhikvadze V D, Kuz'min I V, Pan'shin G A, Bogdanova L N
Med Radiol (Mosk). 1984 Oct;29(10):53-5.
An analysis of short- and long-term results of the combined treatment of tumors of the trachea and adjacent organs with the involvement of the trachea in 100 patients suggests that this method holds promise. In 41 patients the irradiation phase preceded operation, in the rest of 59 patients it followed operation. Radiotherapy was performed daily, 5 fractions every week at a single focal dose of 2-3 Gy. The summary focal dose was 36-48 Gy, for some of the patients 70-80 Gy. Adjuvant radiotherapy did not prevent the performance of complex reconstructive plastic operations with circular, distal or window resection of the trachea. Postoperative complications occurred in 16%, lethal outcome in 4%. Five-year survival following the combined treatment of tracheal tumors was observed in 57%.
对100例气管及相邻器官肿瘤合并气管受累患者进行联合治疗的短期和长期结果分析表明，该方法具有前景。41例患者在手术前进行了放疗阶段，其余59例患者在手术后进行了放疗。放疗每天进行，每周5次分割，单次局部剂量为2 - 3 Gy。总局部剂量为36 - 48 Gy，部分患者为70 - 80 Gy。辅助放疗并不妨碍进行气管环形、远端或开窗切除的复杂重建整形手术。术后并发症发生率为16%，致死率为4%。气管肿瘤联合治疗后的5年生存率为57%。
