Gomazkov O A, Shimkovich M V
Biull Eksp Biol Med. 1975 Jul;80(7):6-9.
A study was made of the influence of ciproheptadin, serotonin and histamine inhibitor, on the effects of exo- and endogenous bradykinin. Ciproheptadin inhibited the effect of bradykinin on a section of a guinea pig intestine in vitro, eliminated the hypotensive effect of bradykinin in rats in vivo, and also blocked the constriction of the vessels of the ear in rabbit and a fall of the blood kininogen level caused by the administration of pyrogenal.
对血清素和组胺抑制剂赛庚啶对外源性和内源性缓激肽作用的影响进行了一项研究。赛庚啶在体外抑制缓激肽对豚鼠肠段的作用，在体内消除缓激肽对大鼠的降压作用，还能阻断兔子耳部血管的收缩以及由注射热原引起的血液激肽原水平下降。
