Catapano F, Portaleone P, Ferretti C, Fornaca G F, Liberali L, Giuliani G C, Verdun di Cantogno L
Minerva Med. 1984 Oct 20;75(40):2361-7.
The effect of road noise on blood catecholamines, cAMP and certain cardiovascular and metabolic parameters was studied in a group of young untreated essential hypertensives. It was found that the 10' stimulus increased both systolic and diastolic pressure values. Blood catecholamines rose only after 5'. The most significant increase was in adrenaline as opposed to noradrenaline and dopamine. Significant changes were noted in cAMP and triacylglycerols (10' and 15' after commencement of the stimulus respectively). Comparison with previous results in normotensives suggested that the catecholamine response to stress is primarily alpha-receptorial when blood pressure is normal and beta-adrenergic in hypertension.
在一组未经治疗的年轻原发性高血压患者中，研究了道路噪声对血液儿茶酚胺、环磷酸腺苷（cAMP）以及某些心血管和代谢参数的影响。结果发现，10分钟的刺激使收缩压和舒张压值均升高。血液儿茶酚胺仅在5分钟后升高。与去甲肾上腺素和多巴胺相比，肾上腺素的升高最为显著。在刺激开始后10分钟和15分钟时，cAMP和三酰甘油出现了显著变化。与之前在血压正常者中的结果相比表明，在血压正常时，儿茶酚胺对应激的反应主要是α受体介导的，而在高血压时则是β肾上腺素能介导的。
