• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

酿酒酵母中串联排列的可变5S核糖体RNA基因。

Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae.

作者信息

McMahon M E, Stamenkovich D, Petes T D

出版信息

Nucleic Acids Res. 1984 Nov 12;12(21):8001-16. doi: 10.1093/nar/12.21.8001.

DOI:10.1093/nar/12.21.8001
PMID:6095183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC320265/
Abstract

Most of the ribosomal RNA genes of the yeast Saccharomyces cerevisiae are about 9 kilobases (kb) in size and encode both the 35S rRNA (processed to produce the 25S, 18S, and 5.8S species) and 5S rRNA. These genes are arranged in a single tandem array of 100 repeats. Below, we present evidence that at the centromere-distal end of this array is a tandem arrangement of a different type of rRNA gene. Each of these repeats is 3.6 kb in length and encodes a single 5S rRNA. The coding sequence of this gene is different from that of the "normal" 5S gene in three positions located at the 3' end of the gene.

摘要

酿酒酵母的大多数核糖体RNA基因大小约为9千碱基(kb),编码35S rRNA(加工后产生25S、18S和5.8S种类)和5S rRNA。这些基因排列成一个由100个重复序列组成的单一串联阵列。下面,我们提供证据表明,在该阵列的着丝粒远端是一种不同类型rRNA基因的串联排列。这些重复序列中的每一个长度为3.6 kb,编码单个5S rRNA。该基因的编码序列在位于基因3'端的三个位置与“正常”5S基因不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/dd91810d2e42/nar00339-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/3b8f6dad2619/nar00339-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/064ca32c284f/nar00339-0053-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/dd91810d2e42/nar00339-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/3b8f6dad2619/nar00339-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/064ca32c284f/nar00339-0053-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f7/320265/dd91810d2e42/nar00339-0055-a.jpg

相似文献

1
Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae.酿酒酵母中串联排列的可变5S核糖体RNA基因。
Nucleic Acids Res. 1984 Nov 12;12(21):8001-16. doi: 10.1093/nar/12.21.8001.
2
A minor class of 5S rRNA genes in Saccharomyces cerevisiae X2180-1B, one member of which lies adjacent to a Ty transposable element.酿酒酵母X2180 - 1B中的一小类5S rRNA基因,其中一个成员位于一个Ty转座元件附近。
Nucleic Acids Res. 1984 May 25;12(10):4083-96. doi: 10.1093/nar/12.10.4083.
3
Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae.酿酒酵母中核糖体RNA基因与单拷贝染色体序列之间连接区域的分析。
Cell. 1982 Feb;28(2):355-64. doi: 10.1016/0092-8674(82)90353-1.
4
Expression of yeast 5S RNA is independent of the rDNA enhancer region.酵母5S RNA的表达独立于核糖体DNA增强子区域。
Nucleic Acids Res. 1990 Jul 25;18(14):4179-84. doi: 10.1093/nar/18.14.4179.
5
5S rRNA genes from Aspergillus nidulans are not transcribed in Saccharomyces cerevisiae.来自构巢曲霉的5S rRNA基因在酿酒酵母中不转录。
Acta Microbiol Pol. 1986;35(3-4):221-5.
6
Does Saccharomyces need an organized nucleolus?酿酒酵母需要一个有组织的核仁吗?
Chromosoma. 1997 Jun;105(7-8):444-51.
7
In vitro transcripts of a yeast variant 5 S rRNA gene exhibit alterations in 3'-end processing and protein binding.酵母变体5 S rRNA基因的体外转录物在3'末端加工和蛋白质结合方面表现出改变。
J Biol Chem. 1987 Oct 15;262(29):13959-65.
8
Cloning and characterisation of the ribosomal RNA genes of the dimorphic yeast, Yarrowia lipolytica.解脂耶氏酵母双态酵母核糖体RNA基因的克隆与鉴定
Curr Genet. 1986;10(6):449-52. doi: 10.1007/BF00419872.
9
Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities.酵母rRNA顺反子间隔区中在体内刺激35S rRNA合成的序列介导RNA聚合酶I依赖性启动子和终止子活性。
Mol Cell Biol. 1989 Mar;9(3):1243-54. doi: 10.1128/mcb.9.3.1243-1254.1989.
10
Isolation and characterization of a Ty element inserted into the ribosomal DNA of the yeast Saccharomyces cerevisiae.插入酿酒酵母核糖体DNA中的Ty元件的分离与鉴定。
Nucleic Acids Res. 1986 Apr 11;14(7):2939-49. doi: 10.1093/nar/14.7.2939.

引用本文的文献

1
Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2.rRNA 加工改变会通过与多聚(A)结合蛋白 Nab2 竞争扰乱核 RNA 内稳态。
Nucleic Acids Res. 2020 Nov 18;48(20):11675-11694. doi: 10.1093/nar/gkaa964.
2
Can too many copies spoil the broth?物极必反?
Microb Cell Fact. 2013 Dec 20;12:128. doi: 10.1186/1475-2859-12-128.
3
5S-rRNA genes in rice embryos.水稻胚胎中的 5S-rRNA 基因。

本文引用的文献

1
Repeated genes in eukaryotes.真核生物中的重复基因。
Annu Rev Biochem. 1980;49:727-64. doi: 10.1146/annurev.bi.49.070180.003455.
2
Orphons: dispersed genetic elements derived from tandem repetitive genes of eucaryotes.孤儿基因:源自真核生物串联重复基因的分散遗传元件。
Cell. 1981 Mar;23(3):651-63. doi: 10.1016/0092-8674(81)90428-1.
3
Collection of published 5S and 5.8S ribosomal RNA sequences.已发表的5S和5.8S核糖体RNA序列的收集。
Plant Mol Biol. 1987 Sep;9(5):443-51. doi: 10.1007/BF00015876.
4
Nuclear RNA surveillance in Saccharomyces cerevisiae: Trf4p-dependent polyadenylation of nascent hypomethylated tRNA and an aberrant form of 5S rRNA.酿酒酵母中的核RNA监测:Trf4p依赖的新生低甲基化tRNA和异常形式的5S rRNA的多聚腺苷酸化
RNA. 2006 Mar;12(3):508-21. doi: 10.1261/rna.2305406. Epub 2006 Jan 23.
5
Molecular and cytogenetic organization of the 5S ribosomal DNA array in chicken (Gallus gallus).鸡(原鸡)5S核糖体DNA阵列的分子和细胞遗传学组织
Chromosome Res. 2003;11(4):305-17. doi: 10.1023/a:1024008522122.
6
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.酿酒酵母第十二号染色体的核苷酸序列。
Nature. 1997 May 29;387(6632 Suppl):87-90.
7
5 S rRNA is involved in fidelity of translational reading frame.5S核糖体RNA参与翻译阅读框的保真度。
Genetics. 1995 Sep;141(1):95-105. doi: 10.1093/genetics/141.1.95.
8
Architecture of a yeast U6 RNA gene promoter.酵母U6 RNA基因启动子的结构
Mol Cell Biol. 1993 May;13(5):3015-26. doi: 10.1128/mcb.13.5.3015-3026.1993.
9
Multiple nucleosome positioning with unique rotational setting for the Saccharomyces cerevisiae 5S rRNA gene in vitro and in vivo.酿酒酵母5S rRNA基因在体外和体内具有独特旋转设置的多个核小体定位
Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9315-9. doi: 10.1073/pnas.90.20.9315.
10
TFIIIB placement on a yeast U6 RNA gene in vivo is directed primarily by TFIIIC rather than by sequence-specific DNA contacts.在体内,TFIIIB在酵母U6 RNA基因上的定位主要由TFIIIC引导,而非通过序列特异性DNA接触。
Mol Cell Biol. 1995 Mar;15(3):1455-66. doi: 10.1128/MCB.15.3.1455.
Nucleic Acids Res. 1984;12 Suppl(Suppl):r133-66. doi: 10.1093/nar/12.suppl.r133.
4
A minor class of 5S rRNA genes in Saccharomyces cerevisiae X2180-1B, one member of which lies adjacent to a Ty transposable element.酿酒酵母X2180 - 1B中的一小类5S rRNA基因,其中一个成员位于一个Ty转座元件附近。
Nucleic Acids Res. 1984 May 25;12(10):4083-96. doi: 10.1093/nar/12.10.4083.
5
Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae.酿酒酵母中核糖体RNA基因与单拷贝染色体序列之间连接区域的分析。
Cell. 1982 Feb;28(2):355-64. doi: 10.1016/0092-8674(82)90353-1.
6
Sequencing end-labeled DNA with base-specific chemical cleavages.通过碱基特异性化学切割对末端标记的DNA进行测序。
Methods Enzymol. 1980;65(1):499-560. doi: 10.1016/s0076-6879(80)65059-9.
7
The redundancy of ribosomal and transfer RNA genes in Saccharomyces cerevisiae.酿酒酵母中核糖体RNA基因和转运RNA基因的冗余性。
J Mol Biol. 1969 Mar 14;40(2):261-77. doi: 10.1016/0022-2836(69)90474-4.
8
A complementation analysis of the restriction and modification of DNA in Escherichia coli.大肠杆菌中DNA限制与修饰的互补分析。
J Mol Biol. 1969 May 14;41(3):459-72. doi: 10.1016/0022-2836(69)90288-5.
9
Repetitive sequences in isolated Thomas circles from Drosophila melanogaster.从黑腹果蝇中分离出的托马斯环中的重复序列。
Cold Spring Harb Symp Quant Biol. 1974;38:371-81. doi: 10.1101/sqb.1974.038.01.040.
10
Detection of specific sequences among DNA fragments separated by gel electrophoresis.在通过凝胶电泳分离的DNA片段中检测特定序列。
J Mol Biol. 1975 Nov 5;98(3):503-17. doi: 10.1016/s0022-2836(75)80083-0.