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[促肾上腺皮质激素在大鼠出生后个体发育中的功能作用]

[Functional role of adrenocorticotropin in the postnatal ontogenesis of rats].

作者信息

Shaliapina V G, Chemyrtan N A

出版信息

Probl Endokrinol (Mosk). 1984 Sep-Oct;30(5):71-4.

PMID:6095258
Abstract

It has been demonstrated by radioimmunoassay that blood ACTH content in young rats substantially rises during eye opening, maximal motor activity, and formation of the vegetative component of the orientation research activity. Under the conditions of an "open field", adrenocorticotropic activity in young rats increases to a greater degree than that in adult animals. This is especially demonstrable during the period of the maximal motor activity (day 16 of postnatal ontogenesis) and the period of nesting completion (day 28). It is concluded that ACTH plays an important functional role in the organization of the adaptive behavior in postnatal ontogenesis of rats.

摘要

放射免疫测定法已证明,幼鼠睁眼、最大运动活动以及定向探究活动的植物性成分形成期间,其血液促肾上腺皮质激素(ACTH)含量大幅上升。在“旷场”条件下,幼鼠的促肾上腺皮质激素活性比成年动物增加得更多。这在最大运动活动期(出生后个体发育第16天)和筑巢完成期(第28天)尤为明显。由此得出结论,促肾上腺皮质激素在大鼠出生后个体发育过程中适应性行为的组织中发挥重要的功能作用。

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