Zubova O B, Buduk-ool L K
Zh Evol Biokhim Fiziol. 1982 May-Jun;18(3):310-3.
Studies have been made of the effect of ACTH fragment 4-7 on learning in rats in early postnatal ontogenesis, as well as of the possibility of preservation of early learning during administration of this peptide to adult animals. It was shown that conditioned reaction of active avoidance practically cannot be formed in normal 13-15-day animals; however, administration of ACTH 4-7 increases the number of animals exhibiting adequate reactions. Weak effect of ACTH 4-7 in 12-15-day animals, in older ones (20-24 days) is changed by a significant stimulating effect.
已经对促肾上腺皮质激素片段4-7对新生大鼠早期个体发育中学习的影响进行了研究，以及对成年动物施用该肽期间早期学习得以保留的可能性进行了研究。结果表明，在正常的13-15日龄动物中几乎无法形成主动回避条件反应；然而，施用促肾上腺皮质激素4-7会增加表现出适当反应的动物数量。促肾上腺皮质激素4-7在12-15日龄动物中的作用较弱，在年龄较大的动物（20-24日龄）中则会产生显著的刺激作用。
