Hesseling P B, Girdle-Brown B, Oosthuysen E, Smit J
S Afr Med J. 1984 Dec 15;66(24):917-8.
Forty-two patients in the acute phase of onyalai were admitted to hospital and randomly divided into three groups of 14 to receive prednisolone 3 mg/kg/d for 1 week, intravenous gammaglobulin 100 mg/kg on 2 successive days, or ascorbic acid 1000 mg 3 times a day for 1 week. The groups were comparable with regard to sex and age distribution, initial platelet counts and initial haemoglobin values. No statistical difference was observed between the three treatment groups with regard to changes in the platelet counts during the period of observation. One patient died from haemorrhagic shock. The low mortality rate in this series suggests that admission to hospital and early correction of blood loss are important factors in reducing the mortality rate associated with onyalai.
42名处于奥尼拉病毒病急性期的患者入院，并随机分为三组，每组14人，分别接受以下治疗：泼尼松龙3毫克/千克/天，持续1周；连续2天静脉注射丙种球蛋白100毫克/千克；或维生素C 1000毫克，每天3次，持续1周。三组在性别、年龄分布、初始血小板计数和初始血红蛋白值方面具有可比性。在观察期内，三个治疗组之间的血小板计数变化没有统计学差异。1例患者死于失血性休克。该系列中的低死亡率表明，入院和早期纠正失血是降低与奥尼拉病毒病相关死亡率的重要因素。
