Rampling R, Catterall M
Clin Oncol. 1984 Dec;10(4):345-51.
The treatment of malignant parotid gland tumours by either surgery or X-radiotherapy alone results in unacceptably high rates of local recurrence. This has led to a combined management, with radiation given either before or after surgery. In the best series this gives an 85% control rate but with severance of the facial nerve in a high proportion of cases. Fast neutron therapy was given for much more advanced tumours and gave the same control rate. Where the facial nerve had been damaged by the tumour, paralysis was lessened substantially in four of nine cases. However neutrons were the apparent course of damage to the nerve in three cases. Two of these had previously received surgery and X-ray therapy.
单独通过手术或X线放射疗法治疗恶性腮腺肿瘤会导致局部复发率高得令人难以接受。这促使人们采用联合治疗方法,即在手术前或手术后进行放疗。在最佳的治疗系列中,联合治疗的控制率为85%,但在很大比例的病例中会切断面神经。快中子疗法用于治疗更晚期的肿瘤,控制率相同。在肿瘤已损伤面神经的病例中,9例中有4例面神经麻痹症状明显减轻。然而,有3例中神经损伤明显是由中子导致的。其中2例此前接受过手术和X线治疗。