Nyberg G, Blomqvist A
J Comp Neurol. 1984 Nov 20;230(1):99-109. doi: 10.1002/cne.902300109.
The projection of muscle afferent fibres to the medulla oblongata and upper spinal cord was studied in the cat by using transganglionic transport of wheat germ agglutinin-horseradish peroxidase conjugate. The results demonstrate a precise, musculotopic termination pattern in the external cuneate nucleus; thus, fibres from the intrinsic muscles of the paw terminate medially; those from forearm, arm, and shoulder muscles terminate progressively more laterally; and those from neck and thoracic muscles terminate in the ventrolateral and dorsolateral parts, respectively. Muscle afferent fibres to the main cuneate nucleus terminate in the ventral "reticular" region of the nucleus, with a sparse projection also to the ventral part of the rostral and caudal regions, including the base of the dorsal horn. Fibres from the neck muscles terminate slightly more laterally in the ventral region than do those from the limb muscles, but otherwise, and thus contrary to the case in the external cuneate nucleus, no topographic organization was detected. In the spinal cord, projection was found to laminae I and V, and from the musculature of the back of the neck to the central cervical nucleus.
通过使用小麦胚凝集素 - 辣根过氧化物酶共轭物的跨神经节运输，在猫身上研究了肌肉传入纤维向延髓和脊髓上部的投射。结果表明，在楔外核中存在精确的肌肉定位终止模式；因此，来自爪内肌的纤维在内侧终止；来自前臂、手臂和肩部肌肉的纤维逐渐向外终止；来自颈部和胸部肌肉的纤维分别终止于腹外侧和背外侧部分。向楔主核的肌肉传入纤维在该核的腹侧“网状”区域终止，也有稀疏投射到吻侧和尾侧区域的腹侧部分，包括背角基部。来自颈部肌肉的纤维在腹侧区域比来自肢体肌肉的纤维稍向外终止，但除此之外，与楔外核的情况相反，未检测到拓扑组织。在脊髓中，发现投射到Ⅰ层和Ⅴ层，并且从颈后部肌肉投射到颈中央核。
