Mel'nichenko E M, Kolomiets N D, Mikhaĭlovskaia V P, Kolomiets A G
Vopr Virusol. 1984 Sep-Oct;29(5):572-5.
Specimens of mixed untreated saliva from 3 groups of children were tested for antibodies to herpes virus by the fluorescent antibody technique (33 children with acute herpes stomatitis, 64 with recurrent herpes stomatitis, and 30 in the control group). Herpes virus antibodies were found in the saliva in 27.2 +/- 7.7% of the cases at the peak of acute stomatitis and in 77.7 +/- 10.0% of cases in the period of epithelization, in 84.6 +/- 10.0% of the examined subjects the antibodies were detected 2-4 months after the disease. Examinations of 64 saliva specimens obtained from the children during one of the relapses of chronic stomatitis demonstrated antibodies more frequently (59.3 +/- 8.0%) than in children at the peak of acute stomatitis disease. A trend for increased antibody content in the saliva of children by the period of epithelization of lesions in the buccal cavity both in acute stomatitis and during relapses of chronic disease was observed. No herpes antibodies were found in saliva specimens from 30 children of the control group.
采用荧光抗体技术对3组儿童未经处理的混合唾液样本进行了疱疹病毒抗体检测（33名患有急性疱疹性口炎的儿童、64名患有复发性疱疹性口炎的儿童以及30名对照组儿童）。在急性口炎高峰期，27.2±7.7%的病例唾液中发现疱疹病毒抗体，在上皮化期，77.7±10.0%的病例唾液中发现该抗体，84.6±10.0%的受检者在疾病发生2 - 4个月后检测到抗体。对64例慢性口炎复发期儿童的唾液样本进行检测，结果显示抗体检出率（59.3±8.0%）高于急性口炎高峰期的儿童。观察到无论是急性口炎还是慢性病复发期，在口腔病变上皮化期儿童唾液中的抗体含量均有增加趋势。对照组30名儿童的唾液样本中未发现疱疹抗体。
