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对具有高比例缺氧肿瘤细胞的实验性肾肿瘤进行增殖动力学检查(作者译)

[Proliferation kinetic examinations on an experimental renal tumour with high portion of hypoxic tumour cells (author's transl)].

作者信息

Kob D, Stiller K J, Kloetzer K H

出版信息

Radiobiol Radiother (Berl). 1977;18(6):725-33.

PMID:609736
Abstract

By autoradiographic examination by means of pulse labelling with 3H-thymidine cell cycle times were determined in solid Ehrlich carcinomas (early carcinomas) in order to obtain comparative values for irradiated tumours. The subcells of the initially labelled cells near the capillaries were found to distribute themselves in the course of 48 h over the whole tumour and to emigrate to hypoxic tumour areas.

摘要

通过用³H - 胸腺嘧啶核苷进行脉冲标记的放射自显影检查,测定了艾氏实体癌(早期癌)的细胞周期时间,以便获得照射肿瘤的比较值。发现靠近毛细血管的最初标记细胞的亚细胞在48小时内分布到整个肿瘤,并迁移到缺氧的肿瘤区域。

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