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[移植后骨营养不良的发病率:基本概况与骨科问题]

[Incidence of osteodystrophy after transplantation: basic outlines and orthopedic problems].

作者信息

Giraldi A, Ciarambino A

出版信息

Chir Ital. 1982 Jun;34(3):445-54.

PMID:6097367
Abstract

The generic term "Renal Osteodystrophy" is used to denote a complex of skeletal and metabolic impairments found in nephropathic patients. Neither dialytic treatment nor transplant is always capable of limiting the worsening evolution; transplantation, on the contrary, while it does not in many cases bring the phospho-calcic metabolism back to full normality, introduces new elements of imbalance arising as a result of the inevitable immunosuppressive therapy. After outlining the main post-transplant metabolic problems, the Authors discuss the manifestations of orthopaedic interest, in particular the most severe complication, i.e. aseptic necrosis.

摘要

通用术语“肾性骨营养不良”用于表示肾病患者中发现的骨骼和代谢损伤的复合体。透析治疗和移植都不一定能够限制病情的恶化发展;相反,移植虽然在许多情况下并不能使磷钙代谢完全恢复正常,但会引入因不可避免的免疫抑制治疗而产生的新的失衡因素。在概述了移植后主要的代谢问题后,作者讨论了骨科关注的表现,特别是最严重的并发症,即无菌性坏死。

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