Narita M, Osada M, Fukusho A
Natl Inst Anim Health Q (Tokyo). 1983 Summer;23(2):61-6.
Ten 2-day-old piglets were inoculated intranasally with Aujeszky's disease virus and their solar ganglia were examined by light and electron microscopy. The cytopathic change noticed was neuronal and glial cell degeneration. It was invariably associated with the virus replicated within the cells. All the main stages of virus development were observed in the degenerated ganglionic cells. Characteristically, plexiform vermicellar array and electron-dense tubular filaments were detected in a part of the nuclei of the infected neuron.
十只2日龄仔猪经鼻内接种奥耶斯基氏病病毒,并通过光学显微镜和电子显微镜检查其腹腔神经节。观察到的细胞病变是神经元和神经胶质细胞变性。这始终与细胞内复制的病毒有关。在变性的神经节细胞中观察到了病毒发育的所有主要阶段。特征性地,在受感染神经元的部分细胞核中检测到丛状蠕虫状阵列和电子致密管状细丝。