Gyarmati J, Földes I, Varga S, Kiss I, Kern M, Gyarmati J
Z Orthop Ihre Grenzgeb. 1984 Nov-Dec;122(6):863-8.
The effect of six-months rachitic diet on the articular cartilage of 12 white Whistar male rats has been studied using light, polarisation, and electronmicroscopes. On the basis of our observations radical changes could be noticed. The intracellular accumulation of glycogen and lipid and the necrosis of cells in the proof/inner/zone indicate the modifications of the cell's structure. The effect of permanent diet on the ground substance of articular cartilage was identified by irregular collagen fibers, and quantitative and qualitative changes of GAGs. On the basis of several author's argumentations it can be supposed that different illness/insufficiency of liver and kidney, and disturbance of resorption in human/can induce similar changes of articular cartilage which was produced by a long term rachitic diet. The cytological picture after long lasting rachitic diet is comparable with the arthrosis.
利用光学显微镜、偏光显微镜和电子显微镜,研究了6个月佝偻病饮食对白化Wistar雄性大鼠关节软骨的影响。基于我们的观察,可以注意到显著变化。糖原和脂质的细胞内积累以及软骨深层/内层/带细胞的坏死表明细胞结构发生了改变。长期饮食对关节软骨基质的影响表现为胶原纤维不规则,以及糖胺聚糖的定量和定性变化。基于几位作者的论证,可以推测,人类肝脏和肾脏的不同疾病/功能不全以及吸收障碍/可能会导致与长期佝偻病饮食引起的关节软骨类似的变化。长期佝偻病饮食后的细胞学图像与关节炎相似。