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膳食补充C 18:3(n-3)对大鼠大脑脂肪酸组成的影响。

Effect of C 18:3 (n-3) dietary supplementation on the fatty acid composition of the rat brain.

作者信息

Cocchi M, Pignatti C, Carpigiani M, Tarozzi G, Turchetto E

出版信息

Acta Vitaminol Enzymol. 1984;6(3):151-6.

PMID:6098183
Abstract

Weanling rats have been fed different diets containing hydrogenated coconut oil or a mixture of grapestone + linseed oil as dietary fats. Groups of 12 animals have been sacrificed at weanling or after 60 or 120 days of this dietary treatment. Body and brain weight, brain total lipids, phospholipids, cholesterol, cerebroside, fatty acid content and fatty acid composition have been evaluated. The diet rich in alphalinolenic acid (C 18:3 n-3) induced a significant increase of the n-3 polyunsaturated fatty acids (C 22:5 and C 22:6, n-3) in the brain, with respect to the other experimental conditions.

摘要

已用含有氢化椰子油或葡萄籽油+亚麻籽油混合物作为膳食脂肪的不同饮食喂养断奶大鼠。每组12只动物在断奶时或这种饮食处理60天或120天后被处死。已评估了体重、脑重、脑总脂质、磷脂、胆固醇、脑苷脂、脂肪酸含量和脂肪酸组成。与其他实验条件相比,富含α-亚麻酸(C 18:3 n-3)的饮食使脑中n-3多不饱和脂肪酸(C 22:5和C 22:6,n-3)显著增加。

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