Krzywicka E, Skopińska E, Wasik M, Tupalska B, Zaleska-Rutczyńska Z
Arch Immunol Ther Exp (Warsz). 1976;24(3):391-4.
A single injection of 10 mg of alpha-globulin fraction isolated from calf serum prolonged survival of skin allografts in mice provided the preparation was injected two days before grafting. An immunosuppressive effect was also obtained by injecting alpha-globulin in a total dose of 13 mg in the second week after grafting in mice pretreated with antithymocyte serum; On the other hand, such an effect was not obtained when alpha-globulin was injected in the early days after grafting in doses of up to 25 mg per mouse.
从小牛血清中分离出的10毫克α球蛋白组分单次注射,可延长小鼠同种异体皮肤移植的存活时间,前提是在移植前两天注射该制剂。在用抗胸腺细胞血清预处理的小鼠中,在移植后第二周注射总剂量为13毫克的α球蛋白也可获得免疫抑制效果;另一方面,在移植后的早期,以每只小鼠高达25毫克的剂量注射α球蛋白时,并未获得这种效果。