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[头孢曲松在儿童感染中的临床评估]

[Clinical evaluation of ceftriaxone in pediatric infections].

作者信息

Ohnuma M, Watanabe A

出版信息

Jpn J Antibiot. 1984 Nov;37(11):2015-20.

PMID:6098697
Abstract

Ceftriaxone (Ro 13-9904, CTRX) was evaluated in 20 children with a suspicion of bacterial infections, 18 were shown to be effective (efficacy rate, 90%). The diagnosis included upper respiratory tract infection (3), bronchitis (3), pneumonia (8) and urinary tract infection (6). The etiologic pathogens isolated were S. pneumoniae (1), and enteropathogenic E. coli (6). These strains were eradicated after treatment. No severe adverse reaction was encountered with the CTRX therapy. The data suggest that CTRX is an effective and safe parenteral antibiotic in the treatment of susceptible pediatric bacterial infections.

摘要

对20名疑似细菌感染的儿童使用头孢曲松(Ro 13 - 9904,CTRX)进行评估,其中18名显示有效(有效率90%)。诊断包括上呼吸道感染(3例)、支气管炎(3例)、肺炎(8例)和尿路感染(6例)。分离出的病原体为肺炎链球菌(1例)和致病性大肠杆菌(6例)。这些菌株在治疗后被清除。CTRX治疗未出现严重不良反应。数据表明,CTRX是治疗易感儿童细菌感染的一种有效且安全的注射用抗生素。

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