Uchida T, Matsuda S, Kimura H, Satoh T, Ishibashi T, Kokubun K, Umezu H, Horikawa A, Saitoh T, Sakauchi Y
Jpn J Antibiot. 1984 Dec;37(12):2506-18.
Clinical evaluation of cefmenoxime (CMX, Bestcall) was examined in the infection associated with hematological disorders, respiratory tract and other disorders. Clinical effectiveness for severe infection of hematological disorders was 47.4% in good and 84.2% in fair response, however, in the respiratory tract infections, 89.7% in good response was obtained. Opportunistic infection due to Gram-negative bacilli are often experienced in patients with hematological disorders. It was discussed that CMX would be a good therapeutic agent against infectious diseases associated with hematological disorders because it's antibacterial spectrum would be parallel to pathogens of such disorders.
对头孢甲肟(CMX,Bestcall)进行了临床评估,涉及血液系统疾病、呼吸道疾病及其他疾病相关的感染。在血液系统疾病严重感染中,临床有效率为良好反应占47.4%,中等反应占84.2%;然而,在呼吸道感染中,良好反应率达89.7%。血液系统疾病患者常发生革兰氏阴性杆菌引起的机会性感染。讨论认为,CMX将是治疗与血液系统疾病相关传染病的良好药物,因为其抗菌谱与此类疾病的病原体相符。