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头孢甲肟在内科的临床评价,特别涉及与血液系统疾病相关的感染

[Clinical evaluation of cefmenoxime in internal medicine, with special reference to infections associated with hematological disorders].

作者信息

Uchida T, Matsuda S, Kimura H, Satoh T, Ishibashi T, Kokubun K, Umezu H, Horikawa A, Saitoh T, Sakauchi Y

出版信息

Jpn J Antibiot. 1984 Dec;37(12):2506-18.

PMID:6098743
Abstract

Clinical evaluation of cefmenoxime (CMX, Bestcall) was examined in the infection associated with hematological disorders, respiratory tract and other disorders. Clinical effectiveness for severe infection of hematological disorders was 47.4% in good and 84.2% in fair response, however, in the respiratory tract infections, 89.7% in good response was obtained. Opportunistic infection due to Gram-negative bacilli are often experienced in patients with hematological disorders. It was discussed that CMX would be a good therapeutic agent against infectious diseases associated with hematological disorders because it's antibacterial spectrum would be parallel to pathogens of such disorders.

摘要

对头孢甲肟(CMX,Bestcall)进行了临床评估,涉及血液系统疾病、呼吸道疾病及其他疾病相关的感染。在血液系统疾病严重感染中,临床有效率为良好反应占47.4%,中等反应占84.2%;然而,在呼吸道感染中,良好反应率达89.7%。血液系统疾病患者常发生革兰氏阴性杆菌引起的机会性感染。讨论认为,CMX将是治疗与血液系统疾病相关传染病的良好药物,因为其抗菌谱与此类疾病的病原体相符。

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